Coquard R, Ginestet C, Sentenac I, Carrie C, Gérard J P
Service d'oncologie-radiothérapie, centre hospitalier Lyon-Sud, Pierre-Bénite, France.
Bull Cancer Radiother. 1995;82(1):40-50.
Conformal radiation therapy represents a considerable and attractive challenge in oncology. Its aim is mainly to improve local control by increasing the dose with an acceptable rate of complications. This work overviews the world literature on this subject. The technical and theoretical requirements are highlighted. These requirements include a precise definition of the target volume by digital imaging (essentially CT scan), but also clear view of the target volume and the organs at risk, a specific collimation of the beam, 3-D dose calculations, optimation procedures, and a rigid immobilization of the patient with verification of his position. Moreover, the clinical applications of conformal radiation therapy are reviewed and discussed.
适形放射治疗是肿瘤学领域一项重大且具有吸引力的挑战。其主要目的是通过增加剂量并将并发症发生率控制在可接受范围内来提高局部控制率。本文综述了关于该主题的世界文献。强调了技术和理论要求。这些要求包括通过数字成像(主要是CT扫描)精确界定靶区体积,同时清晰显示靶区体积和危及器官,对射束进行特定准直,进行三维剂量计算、优化程序,以及对患者进行严格固定并验证其位置。此外,还对适形放射治疗的临床应用进行了综述和讨论。