氟哌噻吨对青少年及青年边缘型人格障碍的成功药物治疗：一项初步开放性试验
The successful pharmacological treatment of adolescents and young adults with borderline personality disorder: a preliminary open trial of flupenthixol.
作者信息
Kutcher S, Papatheodorou G, Reiter S, Gardner D
机构信息
Department of Psychiatry, University of Toronto, North York, Ontario, Canada.
出版信息
J Psychiatry Neurosci. 1995 Mar;20(2):113-8.
Borderline personality disorder is a significantly disabling disturbance often arising in adolescents or young adults. In the absence of demonstrated effective treatments in this population, this open prospective study evaluated the effect of low dose (3 mg per day) flupenthixol in 13 rigorously diagnosed adolescents with borderline personality disorder. Therapeutic outcome over eight weeks of treatment assessed across measures of impulsivity, depression/dysphoria, general psychopathology and global functioning showed significant improvement in all spheres. These findings suggest that low dose flupenthixol may have a role to play in the short-term treatment of this population.
边缘性人格障碍是一种严重致残的精神障碍，通常在青少年或年轻成年人中出现。由于该人群缺乏已证实有效的治疗方法，这项开放性前瞻性研究评估了低剂量（每日3毫克）氟哌噻吨对13名经过严格诊断的边缘性人格障碍青少年的疗效。通过对冲动性、抑郁/烦躁不安、一般精神病理学和整体功能等指标进行评估，发现经过八周治疗后，所有方面均有显著改善。这些研究结果表明，低剂量氟哌噻吨可能在该人群的短期治疗中发挥作用。
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