de Groot J M, Kennedy S H
University of Toronto, Ontario, Canada.
J Psychiatry Neurosci. 1995 Mar;20(2):150-4.
Residents involved in clinical research are frequently unprepared for the problems which may arise in relation to the dual roles of clinician-investigator and patient-subject. Common problems for the clinician-investigator will be outlined including: 1. enlisting patients; 2. using treatment one does not necessarily consider first choice; 3. being blind to treatment prescribed; 4. adhering to a fixed treatment protocol; and 5. deciding when to terminate a trial. Possible solutions will also be offered. In addition, the altered role of the patient as subject will also be considered as it affects patient care within trials.
参与临床研究的住院医生常常对临床医生 - 研究者与患者 - 受试者双重角色可能引发的问题毫无准备。文中将概述临床医生 - 研究者常见的问题，包括：1. 招募患者；2. 使用并非自己首选的治疗方法；3. 对所开治疗方案视而不见；4. 严格遵循固定的治疗方案；5. 决定何时终止试验。同时也会给出可能的解决办法。此外，还会探讨患者作为受试者这一角色的转变如何影响试验中的患者护理。
