Cordero P, Solé A
Servicio de Neumología, Hospital Universitario La Fe, Valencia.
Arch Bronconeumol. 1995 Feb;31(2):89-92. doi: 10.1016/s0300-2896(15)30971-6.
A 19-years-old woman with bronchiolitis obliterans organizing pneumonia (BOOP) secondary to inhalation of toxins in the workplace (Ardystil syndrome) and chronic demyelinating disease of the central nervous system is described. The clinical and radiological picture led to suspicion of BOOP and the diagnosis was confirmed by transbronchial biopsy. The diagnosis of chronic demyelinating disease of the central nervous system was based on the presence of signs of transitory neurological dysfunction along with nuclear magnetic resonance images of the brain that were consistent with the clinical evaluation. The temporal and spatial concurrence of the two diseases in our patient suggests that we may be observing either a new syndrome associated with the inhalation of toxic substances or a coincidence of two diseases that are rare in the population we serve.