重组与修复。Ku从末端开始。
Recombination and repair. Ku starts at the end.
作者信息
Troelstra C, Jaspers N G
机构信息
Department of Cell Biology and Genetics, Erasmus University, Rotterdam, The Netherlands.
出版信息
Curr Biol. 1994 Dec 1;4(12):1149-51. doi: 10.1016/s0960-9822(00)00260-8.
PMID:7704585
Abstract
Genetic evidence suggests that the Ku DNA-end-binding protein complex is central to the recombination-based repair of double-strand breaks that protects DNA from radiation and underlies antibody gene rearrangement.
摘要
遗传学证据表明，Ku DNA末端结合蛋白复合体对于基于重组的双链断裂修复至关重要，这种修复可保护DNA免受辐射影响，也是抗体基因重排的基础。
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