修复与重组。如何实现两端相接。
Repair and recombination. How to make ends meet.
作者信息
Roth D B, Lindahl T, Gellert M
机构信息
Department of Microbiology and Immunology, Baylor College of Medicine, Houston, Texas 77030, USA.
出版信息
Curr Biol. 1995 May 1;5(5):496-9. doi: 10.1016/s0960-9822(95)00101-1.
PMID:7583098
Abstract
The repair of double-stranded breaks in DNA and the recombination of antibody gene V(D)J segments share a common pathway involving the Ku protein, which binds DNA ends, and its associated protein kinase.
摘要
DNA双链断裂的修复以及抗体基因V(D)J片段的重组共享一条涉及Ku蛋白及其相关蛋白激酶的共同途径，其中Ku蛋白可结合DNA末端。
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