阿司匹林与抗惊厥药的相互作用。
Aspirin and anticonvulsant interaction.
作者信息
Wali R S, Patil P A
机构信息
Department of Pharmacology, Jawaharlal Nehru Medical College, Belgaum.
出版信息
Indian J Physiol Pharmacol. 1995 Jan;39(1):77-9.
PMID:7705877
Abstract
Aspirin (360 mg/kg, po) per se had anticonvulsant activity in MES model. No effect was observed at lower doses and in other models. Aspirin 216 mg/kg, po (a subanticonvulsant dose) protected animals, receiving subanticonvulsant doses of phenytoin, phenobarbitone and carbamazepine against MES.
摘要
阿司匹林（360毫克/千克，口服）本身在最大电休克（MES）模型中具有抗惊厥活性。在较低剂量下以及在其他模型中未观察到效果。阿司匹林216毫克/千克，口服（低于抗惊厥剂量）可保护接受低于抗惊厥剂量苯妥英钠、苯巴比妥和卡马西平的动物免受MES影响。
Zotero 插件