病理学家在报告宫颈交界性上皮异常和宫颈上皮内瘤变方面的差异。
Pathologist variation in reporting cervical borderline epithelial abnormalities and cervical intraepithelial neoplasia.
作者信息
Creagh T, Bridger J E, Kupek E, Fish D E, Martin-Bates E, Wilkins M J
机构信息
Department of Histopathology and Cytopathology, St Mary's Hospital, London.
出版信息
J Clin Pathol. 1995 Jan;48(1):59-60. doi: 10.1136/jcp.48.1.59.
Abstract
AIMS
To evaluate the interobserver variation in the diagnosis of cervical intraepithelial lesions, including the new category "borderline abnormalities of uncertain significance" (BAUS) which has not been tested before.
METHODS
Biopsy specimens of 122 patients were reviewed by five histopathologists and the diagnoses subjected to kappa statistical analysis.
RESULTS
There was poor interobserver agreement in all categories, particularly between BAUS and normal tissue.
CONCLUSIONS
The current guidelines for the histological diagnosis of cervical intraepithelial neoplasia and BAUS are poorly reproducible.
摘要
目的
评估宫颈上皮内病变诊断中观察者间的差异，包括尚未经过检验的新类别“意义不明确的边界异常”（BAUS）。
方法
五名组织病理学家对122例患者的活检标本进行了复查，并对诊断结果进行kappa统计分析。
结果
所有类别中观察者间的一致性都很差，尤其是BAUS与正常组织之间。
结论
目前宫颈上皮内瘤变和BAUS组织学诊断的指南可重复性较差。
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