Meh D, Denislic M
University Institute of Clinical Neurophysiology, University Medical Centre, Ljubljana, Slovenia.
J Neurol Sci. 1994 Dec 20;127(2):164-9. doi: 10.1016/0022-510x(94)90069-8.
Values for thermal specific and thermal pain thresholds were determined in 150 healthy volunteers, 67 women and 83 men, aged from 10 to 73 years. Warm-cold difference limen, heat pain and cold pain thresholds were assessed at the face, thenar, medial surface of the upper- and forearm, lateral mammary, lateral umbilical, anterior thigh and lateral leg regions, and lateral aspect of the dorsum of the foot. Temperature and pain sensitivity were assessed by the Marstock method. Temperature sensitivity was found obviously age-dependent. The correlation is linear. Women showed greater sensitivity for small temperature changes, reflected as warm-cold difference limen, and for heat pain and cold pain. Great variation of thermal and pain sensitivity of different body parts was significant in all volunteers, irrespective of age and sex. Interindividual variation was also considerable. Small intraindividual variability was found in measurements repeated in 4 consecutive days and after 4 weeks. Body length did not influence thermal and pain perception thresholds. There were no differences found in thermal and pain sensitivity between the left and the right side of the body.
在150名年龄在10至73岁之间的健康志愿者(67名女性和83名男性)中测定了热特异性和热痛阈值。在面部、鱼际、上肢和前臂内侧表面、外侧乳腺、脐外侧、大腿前部和小腿外侧区域以及足背外侧评估温冷差异阈、热痛和冷痛阈值。采用马尔施托克方法评估温度和疼痛敏感性。发现温度敏感性明显依赖于年龄。这种相关性是线性的。女性对小温度变化表现出更高的敏感性,表现为温冷差异阈以及热痛和冷痛。在所有志愿者中,无论年龄和性别,不同身体部位的热和疼痛敏感性存在很大差异均很显著。个体间差异也相当大。在连续4天和4周后重复测量中发现个体内变异性较小。身体长度不影响热和疼痛感知阈值。身体左右两侧的热和疼痛敏感性没有差异。