一种用于监测豚鼠中针对巴氏杆菌科SP组抗体的酶联免疫吸附测定（ELISA）。
An enzyme-linked immunosorbent assay (ELISA) for monitoring antibodies to SP group Pasteurellaceae in guineapigs.
作者信息
Boot R, Thuis H, Bakker R H, Veenema J L
机构信息
Section of Laboratory Animal Microbiology, National Institute of Public Health and Environmental Protection, Bilthoven, The Netherlands.
出版信息
Lab Anim. 1995 Jan;29(1):59-65. doi: 10.1258/002367795780740348.
Cross-reactivity studies with Pasteurellaceae from guineapigs revealed 5 serologically distinct groups, comprising Pasteurella multocida, Sp group bacteria, SP-like bacteria, Pasteurella pneumotropica and an actinobacillus-like bacterium. Guineapig Pasteurellaceae differed serologically from mouse-derived P. pneumotropica NCTC 8284. An enzyme-linked immunosorbent assay (ELISA) using SP group antigen, developed to monitor 'natural' infections by SP group Pasteurellaceae in guineapigs, detected significantly more infection than did cultivation, and was found superior to an ELISA performed with P. pneumotropica NCTC 8284.
对豚鼠巴斯德氏菌科进行的交叉反应性研究揭示了5个血清学上不同的组，包括多杀巴斯德氏菌、Sp组细菌、SP样细菌、嗜肺巴斯德氏菌和一种类放线杆菌。豚鼠巴斯德氏菌科在血清学上与源自小鼠的嗜肺巴斯德氏菌NCTC 8284不同。为监测豚鼠中SP组巴斯德氏菌科的“自然”感染而开发的使用SP组抗原的酶联免疫吸附测定（ELISA）检测到的感染明显多于培养法，并且发现其优于用嗜肺巴斯德氏菌NCTC 8284进行的ELISA。
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