Neurolytic coeliac blockade is an extremely effective palliative treatment for cancer of the upper abdominal viscera. 2. A successful block can be expected in over 80 per cent of patients in expert hands. 3. Coeliac plexus blockade frequently allows patients to reduce their analgesic consumption, with a consequent reduction in drug-induced side-effects. 4. Knowledge of potential side-effects and complications minimises their impact on the patient.