Doldi N, Busacca M, Bombelli F, Sironi L, Ferrari A
Department of Obstetrics and Gynecology, University of Milan, San Raffaele Scientific Institute, Italy.
Gynecol Endocrinol. 1994 Dec;8(4):255-8. doi: 10.3109/09513599409023629.
A patient with a complete form of testicular feminization with normal gonadotropin and high testosterone levels is described here. These findings are in contrast to previous reports that have shown high circulating luteinizing hormone (LH) levels in adults affected by this syndrome. Testicular histology revealed tubular atrophy and hyperplastic Leydig cells which are in accordance with the high testosterone levels and the difficulty in visualization of the testes. Because of the increased risk of gonadal malignancy, a laparoscopic gonadectomy was performed.
本文描述了一名患有完全型睾丸女性化的患者，其促性腺激素水平正常但睾酮水平高。这些发现与之前的报道形成对比，之前的报道显示受该综合征影响的成年人循环促黄体生成素（LH）水平较高。睾丸组织学显示小管萎缩和间质细胞增生，这与高睾酮水平以及睾丸难以可视化相一致。由于性腺恶性肿瘤风险增加，遂进行了腹腔镜性腺切除术。
