Negishi H, Yamada H, Okuyama K, Makinoda S, Fujimoto S
Department of Obstetrics and Gynecology, Hokkaido University School of Medicine, Sapporo, Japan.
Fetal Diagn Ther. 1995 Jan-Feb;10(1):22-5. doi: 10.1159/000264187.
For chronic fetal hypoxia due to maternal Ebstein's anomaly, oxygen was administered daily to the mother by mask for 105 days. At 20 weeks of gestation, umbilical venous blood gases in room air showed pH 7.42, PO2 25.7 mm Hg, PCO2 33.7 mm Hg and O2 saturation 48.7%, and changed to 7.45, 39.1 mm Hg, 25.9 mm Hg and 77.4% on 3 liters/min of oxygen inhalation by mask, respectively. The PO2 of the maternal arterial blood gases increased to 30 mm Hg on oxygen administration at 15 weeks of gestation, but at 25 weeks of gestation the PO2 increased by only about 10 mm Hg. At 30 weeks, intrauterine growth retardation was suspected. Just after the second puncture of the umbilical cord at 31 weeks and 3 days of gestation, 80 bpm fetal bradycardia occurred for several minutes without recovery and emergency cesarean section was done under the general anesthesia.
对于因母亲埃布斯坦畸形导致的慢性胎儿缺氧，每天通过面罩给母亲输氧105天。妊娠20周时，室内空气中脐静脉血气显示pH值7.42、氧分压25.7毫米汞柱、二氧化碳分压33.7毫米汞柱和氧饱和度48.7%，在通过面罩以每分钟3升的速度吸氧时分别变为7.45、39.1毫米汞柱、25.9毫米汞柱和77.4%。妊娠15周吸氧时母亲动脉血气的氧分压升至30毫米汞柱，但妊娠25周时氧分压仅升高约10毫米汞柱。妊娠30周时，怀疑有宫内生长迟缓。在妊娠31周零3天第二次脐带穿刺后不久，胎儿心率出现每分钟80次的心动过缓，持续数分钟未恢复，遂在全身麻醉下进行了紧急剖宫产。
