Dams R
Lab. Analytical Chemistry, University Gent, Belgium.
Biol Trace Elem Res. 1994 Fall;43-45:539-48. doi: 10.1007/BF02917357.
The merits of radiochemical neutron activation analysis (RNAA) and inductively coupled plasma mass spectrometry (ICP-MS) are critically discussed for the determination of trace and ultratrace elements in normal human serum. For RNAA, two semiautomated procedures, allowing the determination of up to 18 elements, are briefly described. ICP-MS has a series of interesting features for the determination of trace elements. Matrix and spectral interferences can mostly be avoided or corrected for. After a simple 5- or 10-fold dilution and addition of an internal standard, more than 20 elements can be measured precisely and accurately.
针对正常人体血清中痕量和超痕量元素的测定，对放射化学中子活化分析（RNAA）和电感耦合等离子体质谱（ICP-MS）的优点进行了批判性讨论。对于RNAA，简要描述了两种半自动化程序，可测定多达18种元素。ICP-MS在痕量元素测定方面具有一系列有趣的特性。基体和光谱干扰大多可以避免或校正。经过简单的5倍或10倍稀释并加入内标后，可精确准确地测定20多种元素。
