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血清甲状腺球蛋白水平阳性且放射性碘扫描阴性的分化型甲状腺癌患者的管理。

Management of patients with differentiated thyroid cancer who have positive serum thyroglobulin levels and negative radioiodine scans.

作者信息

Clark O H, Hoelting T

机构信息

Department of Surgery, UCSF/Mount Zion.

出版信息

Thyroid. 1994 Winter;4(4):501-5. doi: 10.1089/thy.1994.4.501.

DOI:10.1089/thy.1994.4.501
PMID:7711516
Abstract

Most current evidence suggests that patients with papillary or follicular thyroid cancer after total thyroidectomy who are Tg positive (Tg > or = 10 ng/mL) and radioactive iodine scan negative warrant treatment with 100 mCi of 131I with a follow up scan and Tg determination. If isolated focal metastatic deposits are present they should be resected before treatment with radioiodine. Although some physicians might recommend radioiodine treatment only for high risk patients, we would recommend it for all patients with elevated serum Tg levels that increase after TSH stimulation, or until further information becomes available to support a different approach.

摘要

目前的大多数证据表明,全甲状腺切除术后Tg阳性(Tg≥10 ng/mL)且放射性碘扫描阴性的乳头状或滤泡状甲状腺癌患者,应接受100 mCi的131I治疗,并进行后续扫描和Tg测定。如果存在孤立的局灶性转移灶,应在放射性碘治疗前将其切除。尽管一些医生可能仅建议对高危患者进行放射性碘治疗,但我们建议对所有血清Tg水平在TSH刺激后升高的患者进行治疗,或直至有更多信息支持不同的治疗方法。

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