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加德纳综合征

Gardner's syndrome.

作者信息

Perniciaro C

机构信息

Department of Dermatology, Mayo Clinic, Jacksonville, Florida, USA.

出版信息

Dermatol Clin. 1995 Jan;13(1):51-6.

PMID:7712650
Abstract

Gardner's syndrome is an autosomal dominant genodermatosis. Familial polyposis of the colon, osteomas, and cutaneous epidermoid cysts are characteristic features. Colon cancer will develop in all affected individuals unless prophylactic colectomy is performed. The follow-up and management of patients with Gardner's syndrome require a coordinated effort by physicians with expertise in gastroenterology, general surgery, oral surgery, radiology, endocrinology, neurology, ophthalmology, and dermatology. Genetic and psychological counseling should also be available for these patients.

摘要

加德纳综合征是一种常染色体显性遗传性皮肤病。结肠家族性息肉病、骨瘤和皮肤表皮样囊肿是其特征性表现。除非进行预防性结肠切除术,否则所有患病个体都会发展为结肠癌。对加德纳综合征患者的随访和管理需要胃肠病学、普通外科、口腔外科、放射学、内分泌学、神经学、眼科学和皮肤病学等领域的专家共同协作。还应为这些患者提供遗传和心理咨询服务。

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