Zhou X R, Du X G
Obstetrics and Gynecology Hospital, Shanghai Medical University.
Zhonghua Fu Chan Ke Za Zhi. 1994 Oct;29(10):601-3, 637.
The clinicopathological review of 49 cases of the serous borderline tumors (SBTs) of ovary with a follow-up of more than 20 years is presented. The results showed that there were no significant differences in the recurrence and the mortality rates between the SBTs and the SBTs containing foci of stromal microinvasion (P > 0.05). The longterm survival rate of 40 cases with stage I was 97.5%, while stage III decreased to 33.3% (P < 0.01). The cause of 3 deaths was small bowel obstruction. No difference was found in the prognostic status and the mean survival years between total abdominal hysterectomy plus bilateral salpingo oophorectomy and unilateral salpingo-oophorectomy. 5 of 16 cases treated by unilateral salpingo-oophorectomy or cystectomy underwent normal pregnancies and deliveries during the follow-up period. These results suggest that SBTs containing foci of the stromal microinvasion did not affect the prognosis, they may have been taken as a subset of the ovarian SBTs. The malignant potential of SBTs is very low because of their excellent survival and the deaths only due to complications. Treatment should therefore be conservative in stage I cases, particularly in young women who wish for preservation of fertility functions.
本文呈现了对49例卵巢浆液性交界性肿瘤（SBTs）进行的临床病理回顾，随访时间超过20年。结果显示，SBTs与伴有间质微浸润灶的SBTs在复发率和死亡率方面无显著差异（P>0.05）。40例Ⅰ期患者的长期生存率为97.5%，而Ⅲ期患者降至33.3%（P<0.01）。3例死亡原因是小肠梗阻。全腹子宫切除加双侧输卵管卵巢切除术与单侧输卵管卵巢切除术在预后状况和平均生存年限方面未发现差异。16例接受单侧输卵管卵巢切除术或囊肿切除术的患者中，有5例在随访期间正常妊娠并分娩。这些结果表明，伴有间质微浸润灶的SBTs不影响预后，它们可被视为卵巢SBTs的一个亚组。由于SBTs的生存率良好且仅因并发症死亡，其恶性潜能非常低。因此，对于Ⅰ期病例，尤其是希望保留生育功能的年轻女性，治疗应采取保守方式。
