Puppala A R, Steinheber F U
Am J Gastroenterol. 1977 Dec;68(6):578-81.
A patient with fatal submassive hepatic necrosis after methyldopa is described. Patient had positive L.E. cell preparation. The literature and the two previous cases of submassive hepatic necrosis were briefly reviewed. Methyldopa occasionally produces severe hepatitis, chronic active and rarely submassive necrosis.
本文描述了一名服用甲基多巴后发生致命性亚大块肝坏死的患者。患者狼疮细胞检查呈阳性。文章简要回顾了相关文献及之前两例亚大块肝坏死的病例。甲基多巴偶尔会引发严重肝炎、慢性活动性肝炎,很少导致亚大块坏死。