Koek G H, Stricker B H, Veldhuizen R W, de Graaf P
Sint Antoniushove Ziekenhuis, Leidschendam.
Ned Tijdschr Geneeskd. 1991 Jun 15;135(24):1088-90.
The case is described of a patient with fulminant hepatic failure attributed to intake of glafenine 400 mg daily for 15 days. The first symptoms appeared two weeks after discontinuation of glafenine. Other causes of hepatic necrosis could be excluded. Approximately five weeks after the onset of symptoms the patient died of hepatic failure. At autopsy massive hepatic necrosis and massive pancreatic necrosis were demonstrated.
本文描述了一名暴发性肝衰竭患者，其病因是连续15天每天服用400毫克格拉非宁。停药两周后出现最初症状。可排除肝坏死的其他原因。症状出现约五周后，患者死于肝衰竭。尸检显示有大面积肝坏死和大面积胰腺坏死。
