Benoni G, Bellavite P, Adami A, Chirumbolo S, Lippi G, Brocco G, Giulini G M, Cuzzolin L
Institute of Pharmacology, University of Verona, Italy.
Int J Sports Med. 1995 Jan;16(1):34-7. doi: 10.1055/s-2007-972960.
Neutrophils play an important role in the immune system, forming the "first line of defence" against invading microorganisms and there are few data available concerning neutrophil functions in relation to exercise. We investigated in 7 basketball professional players possible changes before, during and after the sports season, in some haematological parameters and in several aspects of the phagocytic process of neutrophils, such as adhesion, superoxide anion release and bactericidal activity. Training and competitions produced a significant rise in the number of total leukocytes and differential counts, but the values returned to the pre-start levels 3 weeks after the end of the championship. The bactericidal activity and the superoxide anion released were significantly greater during the sports season, while the percentage of cellular adhesion significantly decreased during the championship; after the sports season the values returned to the control levels. As in the literature data concerning neutrophil functions in relation to exercise are non-convergent, it is important in our opinion, to understand whether the alterations induced by exercise can persist after repeated stimuli.
中性粒细胞在免疫系统中发挥着重要作用，构成抵御入侵微生物的“第一道防线”，然而关于运动与中性粒细胞功能关系的数据却很少。我们对7名职业篮球运动员在赛季前、赛季中和赛季后的一些血液学参数以及中性粒细胞吞噬过程的几个方面，如黏附、超氧阴离子释放和杀菌活性，进行了调查。训练和比赛使白细胞总数及分类计数显著增加，但在锦标赛结束3周后这些数值恢复到赛前水平。在赛季期间，杀菌活性和释放的超氧阴离子显著增强，而在锦标赛期间细胞黏附百分比显著下降；赛季结束后这些数值恢复到对照水平。由于文献中关于运动与中性粒细胞功能关系的数据并不一致，我们认为了解运动引起的改变在反复刺激后是否会持续很重要。
