Lexchin J
Can Fam Physician. 1997 May;43:941-5.
To assess the information pharmaceutical sales representatives provide to physicians.
A MEDLINE search from January 1966 to May 1996 was done using combinations of the terms pharmaceutical industry, drug information services, drug utilization, physician's practice patterns and prescriptions, and drugs. Studies identified from this search were supplemented by material from my personal library.
Studies had to be conducted in industrialized countries, based on direct observations of actual physician and sales representative contacts, and reporting quantitative results on the quality of information transmitted.
Four studies were included. Representatives usually mentioned the indications for their drugs, but omitted safety information. Representatives' information frequently contained inaccuracies.
Sales representatives present only selected, usually positive, information about their products. Canadian doctors should not be passive recipients of information provided by sales representatives. Physicians who choose to continue to see representatives must critically compare the information they get from them with that contained in scientific publications.
评估药品销售代表向医生提供的信息。
使用制药行业、药品信息服务、药物利用、医生执业模式与处方以及药物等术语组合，对1966年1月至1996年5月期间的MEDLINE进行检索。通过此次检索确定的研究由我个人图书馆的资料进行补充。
研究必须在工业化国家进行，基于对医生与销售代表实际接触的直接观察，并报告所传递信息质量的定量结果。
纳入了四项研究。销售代表通常会提及他们药品的适应证，但会遗漏安全信息。销售代表提供的信息常常不准确。
销售代表仅提供有关其产品的部分信息，且通常是正面信息。加拿大医生不应被动接受销售代表提供的信息。选择继续接待销售代表的医生必须审慎地将从他们那里获得的信息与科学出版物中包含的信息进行比较。
