Rosa N, Cennamo G, Del Prete A, Pastena B, Sebastiani A
Eye Department, University Federico II, Naples, Italy.
Ophthalmologica. 1995;209(1):17-20. doi: 10.1159/000310568.
Photorefractive keratectomy (PRK) with a 193-nm excimer laser has been shown not to destroy endothelial cells in vivo. However, this laser could damage endothelial cell metabolism, and result in damage over a longer term. In this paper, a comparison between the number and shape of corneal endothelial cells has been performed in 25 patients before and 6 months after PRK. These patients underwent treatment with myopic correction ranging from 2.5 to 17 dpt and with an estimated corneal thinning ranging from 25 to 170 microns. No significant changes in the number (p = 0.167) and shape (p = 0.075) of endothelial cells have been found. These results show that there are no long-term damages after PRK even in severely myopic eyes.
已证明，使用193纳米准分子激光进行的光性屈光性角膜切削术（PRK）在体内不会破坏内皮细胞。然而，这种激光可能会损害内皮细胞的新陈代谢，并在较长时期内造成损害。本文对25例患者在PRK术前和术后6个月的角膜内皮细胞数量和形态进行了比较。这些患者接受了2.5至17屈光度的近视矫正治疗，预计角膜变薄范围为25至170微米。未发现内皮细胞数量（p = 0.167）和形态（p = 0.075）有显著变化。这些结果表明，即使是高度近视眼，PRK术后也不会有长期损害。
