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[疫苗疗法在治疗鼻及鼻窦细菌性过敏中的应用]

[Vaccine therapy in the treatment of nasal and sinus bacterial allergies].

作者信息

Ziuzio S, Sakson B

机构信息

Klinicznego Oddziału Otolaryngologicznego Wojskowego Szpitala Klinicznego w Bydgoszczy.

出版信息

Wiad Lek. 1994 Jul;47(13-14):510-3.

PMID:7716937
Abstract

An analysis was performed of the course of nasal and sinus bacterial allergy in 160 children treated in the years 1981-1990 with bacterial vaccines. History data, results of medical examinations and laboratory investigations, indications and contraindications to vaccine therapy, and the methods and results of treatment are presented. Vaccines available in Poland were used--Polyvaccium (nasal and subcutaneous) produced by Biomed, Broncho-Vaxom, IRS-19. As the main criterion of positive results, improvement or regression of clinical manifestations, normalization of immunoglobulin level, and also extinction of organ reactions and generalized and local skin reactions to bacterial allergens, were accepted. Very good and good results were achieved in 63% of the studied patients. The best results were achieved using combined treatment--vaccine therapy, anti-inflammatory drugs, and symptomatic antiallergic treatment (68% of positive results). In comparison to the control group (80 children) in which no vaccine therapy was used, the results obtained in the studied group were statistically significantly better.

摘要

对1981年至1990年间接受细菌疫苗治疗的160名儿童的鼻和鼻窦细菌性过敏病程进行了分析。文中呈现了病史数据、医学检查和实验室调查结果、疫苗治疗的适应证和禁忌证,以及治疗方法和结果。使用了波兰现有的疫苗——由Biomed生产的Polyvaccium(鼻用和皮下注射)、Broncho-Vaxom、IRS-19。作为阳性结果的主要标准,接受了临床表现的改善或消退、免疫球蛋白水平的正常化,以及对细菌过敏原的器官反应和全身性及局部皮肤反应的消失。63%的研究患者取得了非常好和良好的结果。联合治疗——疫苗治疗、抗炎药物和对症抗过敏治疗取得了最佳效果(阳性结果占68%)。与未使用疫苗治疗的对照组(80名儿童)相比,研究组获得的结果在统计学上有显著改善。

相似文献

1
[Vaccine therapy in the treatment of nasal and sinus bacterial allergies].[疫苗疗法在治疗鼻及鼻窦细菌性过敏中的应用]
Wiad Lek. 1994 Jul;47(13-14):510-3.
2
[Clinical evaluation of treating accessory nasal sinus diseases in children using autovaccine].[应用自身疫苗治疗儿童鼻窦疾病的临床评估]
Med Dosw Mikrobiol. 1994;46(1-2 Suppl):67-73.
3
Clinical efficacy of Broncho-Vaxom in adult patients with chronic purulent sinusitis--a multi-centric, placebo-controlled, double-blind study.泛福舒对成年慢性化脓性鼻窦炎患者的临床疗效——一项多中心、安慰剂对照、双盲研究。
Int J Clin Pharmacol Ther Toxicol. 1989 Nov;27(11):530-4.
4
[Immunologic indicators in the treatment of recurrent respiratory diseases using peroral bacterial vaccines].[口服细菌疫苗治疗复发性呼吸道疾病中的免疫指标]
Cesk Pediatr. 1989 Aug;44(8):454-8.
5
[Conservative treatment of chronic sinusitis. Success of oral bacterial lysate therapy].[慢性鼻窦炎的保守治疗。口服细菌溶解产物疗法的成效]
Laryngorhinootologie. 1989 Dec;68(12):671-4. doi: 10.1055/s-2007-998427.
6
Bacterial immunotherapy in bronchial asthma.
Allergol Immunopathol (Madr). 1979 Jan-Feb;7(1):47-54.
7
[Effectiveness of Broncho-Vaxom in prevention of recurrent upper respiratory tract infection in children].[泛福舒在预防儿童复发性上呼吸道感染中的有效性]
Pol Merkur Lekarski. 2005 Nov;19(113):625-9.
8
[Characteristics of the course and treatment of inflammatory nasal and paranasal sinus diseases in pregnancy].[妊娠期鼻及鼻窦炎性疾病的病程及治疗特点]
Vestn Otorinolaringol. 1993 Sep-Dec(5-6):42-5.
9
Broncho-vaxom therapy for children with chronic bronchitis.用泛福舒治疗慢性支气管炎患儿。
Ther Hung. 1989;37(1):28-31.
10
[Broncho-Vax and IRS 19 in the treatment of recurrent respiratory tract inflammation in children].
Cesk Pediatr. 1992 Nov;47(11):666-9.

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World Allergy Organ J. 2010 Aug;3(8 Suppl):S17-23. doi: 10.1097/WOX.0b013e3181ee0cfd.
2
OM-85 BV, an immunostimulant in pediatric recurrent respiratory tract infections: a systematic review.OM-85BV 作为一种免疫刺激剂治疗儿童反复呼吸道感染的系统评价
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