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市售免疫球蛋白中特异性抗体的浓度(作者译)

[Concentration of specific antibodies in commercially avaialable immunoglobulins (author's transl)].

作者信息

Wirsing C H, Finger H, Jansen P, Trobisch H

出版信息

Blut. 1978 Apr 20;36(4):211-6. doi: 10.1007/BF01079952.

Abstract

Not significant differences in the composition or concentration of specific antibodies against microbial antigens could be measured in five commercially available human immunoglobulin preparations for intravenous use. Prediction of prophylactic or therapeutic efficiency of such preparations according to their antibody content seems to be only partially possible. Human immunoglobulins for intravenous use should be free from irregular antibodies against erythrocyte antigens of the Rh-systems, as found in one of the specimens tested.

摘要

在五种市售的静脉用人免疫球蛋白制剂中,未检测到针对微生物抗原的特异性抗体在组成或浓度上的显著差异。根据这些制剂的抗体含量来预测其预防或治疗效果似乎仅部分可行。静脉用人免疫球蛋白应不含针对Rh系统红细胞抗原的不规则抗体,在所检测的一份标本中就发现了此类抗体。

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