Schmücker G, Mitusch R, Stierle U, Giannitsis E, Wucherpfennig H, Sheikhzadeh A, Diederich K W
Klinik für Kardiologie Medizinische Universität, Lübeck.
Z Kardiol. 1995 Feb;84(2):146-53.
Regional wall motion abnormality is the best indicator for coronary ischemia. Myocardial wall motion is registrated by cardiokymography (CKG), a mechanocardiographic method. Because of the high incidence of artefacts, echocardiography and nuclear imaging technique have been preferred. Computer-assisted signal averaging CKG improves practicability and allows measurements during exercise testing. Exercise testing was performed in 54 patients with suspected ischemic heart disease without mitral or aortic valve dysfunction, myocardial infarction or prior cardiac surgery. The results of simultaneously recorded ECG and CKG were compared with coronary angiographic results. CKG sensitivity and specificity were higher than that of ECG (76 and 80% vs 71 and 52%). If diagnosis was based on pathological or nonpathological results of both CKG and ECG, sensitivity and negative predictive value increased to 87 and 83%, respectively. Sensitivity reached 93% when only one pathological result was required. CKG combined with signal-averaging techniques has advanced to become a specific and sensitive tool in the non-invasive diagnostic approach to ischemic heart disease.
局部室壁运动异常是冠状动脉缺血的最佳指标。心肌壁运动通过心动记波图（CKG）进行记录，这是一种机械心动图方法。由于伪像发生率高，超声心动图和核成像技术更受青睐。计算机辅助信号平均CKG提高了实用性，并允许在运动试验期间进行测量。对54例疑似缺血性心脏病且无二尖瓣或主动脉瓣功能障碍、心肌梗死或既往心脏手术史的患者进行了运动试验。将同步记录的心电图和CKG结果与冠状动脉造影结果进行比较。CKG的敏感性和特异性高于心电图（分别为76%和80%，而心电图为71%和52%）。如果诊断基于CKG和心电图的病理或非病理结果，则敏感性和阴性预测值分别提高到87%和83%。当仅需要一个病理结果时，敏感性达到93%。CKG与信号平均技术相结合已发展成为缺血性心脏病无创诊断方法中的一种特异性和敏感性工具。
