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以急性单核细胞白血病告终的B细胞淋巴瘤。

B-cell lymphoma terminating in acute monoblastic leukemia.

作者信息

Muroi K, Imagawa S, Suzuki T, Amemiya Y, Miura Y

机构信息

Department of Transfusion Medicine, Jichi Medical School, Tochigi.

出版信息

Intern Med. 1995 Jan;34(1):36-8. doi: 10.2169/internalmedicine.34.36.

DOI:10.2169/internalmedicine.34.36
PMID:7718977
Abstract

A case of CD11b-, CD14- and CD36-positive B-cell lymphoma terminating in acute monoblastic leukemia is presented. The patient was initially suspected as having angiotrophic lymphoma due to proliferation of lymphoma cells within the sinusoid of the liver and clinical signs. Following chemotherapy, the lymphoma cells were converted into CD11b- and CD36-positive monoblasts. Lineage switching of B-cell lymphoma to acute monoblastic leukemia may have occurred in this case.

摘要

本文报告一例以急性单核细胞白血病告终的CD11b、CD14和CD36阳性B细胞淋巴瘤病例。由于肝血窦内淋巴瘤细胞的增殖及临床症状,该患者最初被怀疑患有血管营养性淋巴瘤。化疗后,淋巴瘤细胞转变为CD11b和CD36阳性的原始单核细胞。该病例可能发生了B细胞淋巴瘤向急性单核细胞白血病的谱系转换。

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