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[绵羊的主要OLA组织相容性复合体。先前通过微量淋巴细胞毒性定义的11个因子的遗传学研究的最新结果]

[The major OLA histocompatibility complex of sheep. Recent results in the genetic study of 11 factors previously defined by microlymphocytotoxicity].

作者信息

Millot P, Dausset J

出版信息

C R Acad Hebd Seances Acad Sci D. 1978 Mar 13;286(10):801-5.

PMID:77194
Abstract

The genetic study of 11 lymphocyte factors previously described in sheep was continued. 9 factors are the products of alleles at two closely linked loci OLA-A and B. The last two factors are the products of two genes at two distinct loci OL-X and OL-Z. Recombinations between the two closely linked loci are very rare (0.6%); but they are frequent between these two loci and OL-X (26%). The OL-Z locus seems to be independent of the two linked loci OLA-A and B. The allele frequencies at the four loci are given.

摘要

对先前已描述的绵羊11种淋巴细胞因子的遗传学研究仍在继续。9种因子是位于两个紧密连锁基因座OLA - A和B上等位基因的产物。最后两种因子是位于两个不同基因座OL - X和OL - Z上的两个基因的产物。两个紧密连锁基因座之间的重组非常罕见(0.6%);但在这两个基因座与OL - X之间重组很频繁(26%)。OL - Z基因座似乎独立于两个连锁基因座OLA - A和B。给出了四个基因座的等位基因频率。

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