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花粉症患者和对照组的细胞组胺释放、特异性和总血清IgE水平。

Cellular histamine release, specific and total serum IgE levels in hay fever patients and controls.

作者信息

Weyer A, David B, Laurent M, Henocq E

出版信息

Clin Allergy. 1978 Mar;8(2):187-94. doi: 10.1111/j.1365-2222.1978.tb00463.x.

DOI:10.1111/j.1365-2222.1978.tb00463.x
PMID:77195
Abstract

The amount of histamine released from blood leucocytes by allergen, the amount of allergen required to release 50% histamine and the total IgE and IgE specific for Dactylis glomerata are compared in nine hay fever patients and five control individuals. The variation with time of total IgE, of specific IgEe and of the percentage of histamine released at a fixed allergen concentration, corresponding to the cellular sensitivity, is shown for one control individual with positive in vitro and skin tests, but without clinical symptoms. For four patients with a low total IgE level the evolution of these parameters during a 1 year treatment period is presented.

摘要

比较了9名花粉症患者和5名对照个体中,变应原从血液白细胞释放的组胺量、释放50%组胺所需的变应原量以及针对鸭茅的总IgE和特异性IgE量。对于一名体外和皮肤试验呈阳性但无临床症状的对照个体,展示了总IgE、特异性IgE以及在固定变应原浓度下释放的组胺百分比随时间的变化情况,该百分比对应细胞敏感性。还呈现了4名总IgE水平较低的患者在1年治疗期内这些参数的变化情况。

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