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[普罗帕酮与维拉帕米中毒。2例临床病例报告]

[Propafenone and verapamil poisoning. Report of 2 clinical cases].

作者信息

Lanari A, Brun M, Dormi A, Giunti M, Mariani A, Mariotti V, Montanari G, Volpe P, Amici R

机构信息

Divisione di Cardiologia, Ospedale Civile di Senigallia.

出版信息

Clin Ter. 1994 Dec;145(12):457-61.

PMID:7720353
Abstract

We described the self-poisoning of two young adolescents who took improper doses of two major cardiovascular drugs: propafenone and verapamil. The young girls developed markedly different clinical patterns: ECG abnormalities without clinical consequences were found in one case progressively ingravescent ECG abnormalities leading to cardiac arrest in the other. These differences are probably due to varying doses taken and metabolic states. Conventional detoxication and resuscitation techniques proved successful in both cases.

摘要

我们描述了两名青少年自我中毒的案例,他们服用了不当剂量的两种主要心血管药物:普罗帕酮和维拉帕米。这两名年轻女孩出现了明显不同的临床症状:一例出现心电图异常但无临床后果,另一例则出现逐渐加重的心电图异常并导致心脏骤停。这些差异可能是由于服用剂量和代谢状态不同所致。在这两个案例中,传统的解毒和复苏技术都被证明是成功的。

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