Bergman A, Svedberg U, Nilsson E
Department of Dermatology, Sundsvall Hospital, Sweden.
Contact Dermatitis. 1995 Jan;32(1):14-7. doi: 10.1111/j.1600-0536.1995.tb00833.x.
This paper presents the case of a non-smoking and non-atopic male, exposed to iridium chloride at work, who developed respiratory tract symptoms and contact urticaria. Application of iridium salt to normal skin caused contact urticaria. An iridium chloride prick test showed a positive reaction and a scratch test produced anaphylactoid reactions. Platinum salt allergy was excluded through prick testing with hexachloroplatinate solution. There is no previous report describing a case where an individual has a positive prick test reaction to iridium salts and simultaneously a negative one to platinum salts. The results are interpreted as immediate-type hypersensitivity (Type I allergy?) to iridium salt. The route of sensitization was probably through the airways. Further testing showed that iridium salt allergy could persist for at least 18 months after exposure ceases. 14 employees at the same factory were prick tested with iridium and platinum salts with negative results. Prick testing is recommended as a method of first choice when investigating a person with suspected iridium salt allergy.
本文介绍了一名不吸烟、非特应性男性的病例，该男性在工作中接触氯化铱后出现呼吸道症状和接触性荨麻疹。将铱盐应用于正常皮肤会引发接触性荨麻疹。氯化铱点刺试验显示阳性反应，划痕试验产生类过敏反应。通过用六氯铂酸溶液进行点刺试验排除了铂盐过敏。此前没有报告描述个体对铱盐点刺试验反应呈阳性而同时对铂盐反应呈阴性的情况。这些结果被解释为对铱盐的速发型超敏反应（I型过敏？）。致敏途径可能是通过呼吸道。进一步检测表明，铱盐过敏在接触停止后可能持续至少18个月。同一家工厂的14名员工用铱盐和铂盐进行了点刺试验，结果均为阴性。在调查疑似铱盐过敏的人员时，推荐将点刺试验作为首选方法。
