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肛周克罗恩病外科治疗的二十年回顾

Twenty-year review of the surgical management of perianal Crohn's disease.

作者信息

Williamson P R, Hellinger M D, Larach S W, Ferrara A

机构信息

Orlando Regional Medical Center, Florida, USA.

出版信息

Dis Colon Rectum. 1995 Apr;38(4):389-92. doi: 10.1007/BF02054227.

Abstract

PURPOSE

A retrospective analysis of 48 patients treated over a 20-year period (March 1973-April 1993) was undertaken to assess the results of our practice of early surgical intervention in suppurative complications of perianal Crohn's disease.

METHODS

All patients were either seen in the office within the last six months or contacted by phone.

RESULTS

The average age of our patients was 30 years at initial diagnosis. Thirty-four patients (71 percent) initially presented with intestinal disease and four (8 percent) with only perianal disease. Thirteen patients (27 percent) initially presented with simultaneous intestinal and perianal disease. The various fistulas at initial presentation included 8 intersphincteric (17 percent), 14 transphincteric (29 percent), 11 complex or multiple (23 percent), 5 rectovaginal (10 percent), and 2 unclassified, for a total of 40 patients. Eight patients (17 percent) presented with only an abscess. Eighty five percent of our patients healed after their first procedure, with an average time to heal of 2.8 months. Thirteen (27 percent) patients had recurrences after initial healing of their wounds. The mean time to recurrence after healing was 5.25 years. Fifty-four percent of our recurrences (7 patients) were treated by incision and drainage of an abscess only. Seven of 13 recurrences healed after the second procedure (54 percent), and 5 of 6 healed after a third procedure (83 percent). Only seven (14 percent) of our patients underwent a proctocolectomy during the study period, through September, 1993. Our overall probability of avoiding proctectomy and healing perineal wounds of 86 percent is consistent with published literature.

CONCLUSIONS

Early aggressive surgical management of suppurative complications of perianal Crohn's disease before complex management problems ensue results in a high incidence of healing and a low risk of subsequent proctectomy.

摘要

目的

对48例在20年期间(1973年3月至1993年4月)接受治疗的患者进行回顾性分析,以评估我们对肛周克罗恩病化脓性并发症进行早期手术干预的效果。

方法

所有患者均在过去六个月内在门诊就诊或通过电话联系。

结果

我们的患者初诊时的平均年龄为30岁。34例患者(71%)初发时为肠道疾病,4例(8%)仅为肛周疾病。13例患者(27%)初发时同时患有肠道和肛周疾病。初诊时的各种瘘管包括8例括约肌间瘘(17%)、14例经括约肌瘘(29%)、11例复杂或多发瘘(23%)、5例直肠阴道瘘(10%)和2例未分类瘘,共有40例患者。8例患者(17%)仅表现为脓肿。85%的患者在首次手术后愈合,平均愈合时间为2.8个月。13例患者(27%)伤口初次愈合后复发。愈合后复发的平均时间为5.25年。我们54%的复发患者(7例)仅通过脓肿切开引流治疗。13例复发患者中有7例在第二次手术后愈合(54%),6例中有5例在第三次手术后愈合(83%)。在研究期间,截至1993年9月,我们只有7例患者(14%)接受了直肠结肠切除术。我们避免直肠切除术和会阴伤口愈合的总体概率为86%,与已发表的文献一致。

结论

在复杂的管理问题出现之前,对肛周克罗恩病化脓性并发症进行早期积极的手术管理,可使愈合率高且后续直肠切除术风险低。

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