Pelc L R, Sayre J, Yun K, Castro L J, Herfkens R J, Miller D C, Pelc N J
Department of Radiology, Stanford University School of Medicine, California, USA.
Invest Radiol. 1994 Dec;29(12):1038-42. doi: 10.1097/00004424-199412000-00005.
The accuracy of myocardial motion measurements, computed from cine-phase contrast (cine-PC) magnetic resonance (MR) velocity data, was compared with directly visualized motion of MR signal voids caused by implanted tantalum markers in anesthetized dogs.
Magnetic resonance imaging (MRI) data were electrocardiogram-gated and divided into 16 phases per cardiac cycle. Myocardial trajectories as a function of time in the cardiac cycle were measured using both methods for four to seven markers in each of eight animals.
The peak observed in-plane excursion was 4.0 +/- 2.1 mm. The average deviation between displacements derived from velocity data versus displacements visualized directly was 1.1 +/- 0.7 mm (27.5% of the peak displacement). The difference was less if three separate MR scans were used to measure each velocity component in the cine-PC method. This improvement is probably caused by improved temporal resolution.
Cine-PC MRI offers a noninvasive method for accurate quantification of myocardial motion.
将从电影相位对比(cine-PC)磁共振(MR)速度数据计算得出的心肌运动测量准确性,与麻醉犬体内植入钽标记物所产生的MR信号空洞的直接可视化运动进行比较。
磁共振成像(MRI)数据采用心电图门控,每个心动周期分为16个阶段。在8只动物中,对每只动物体内4至7个标记物,同时使用两种方法测量心动周期中作为时间函数的心肌轨迹。
观察到的平面内最大偏移为4.0 +/- 2.1毫米。从速度数据得出的位移与直接可视化位移之间的平均偏差为1.1 +/- 0.7毫米(为最大位移的27.5%)。如果在cine-PC方法中使用三次单独的MR扫描来测量每个速度分量,差异会更小。这种改进可能是由于时间分辨率提高所致。
cine-PC MRI提供了一种用于准确量化心肌运动的非侵入性方法。