Department of Internal Medicine II, University Hospital of Ulm, Ulm Germany.
J Cardiovasc Magn Reson. 2011 Oct 12;13(1):59. doi: 10.1186/1532-429X-13-59.
The objective of this study was to investigate the impact of sensitivity encoding on the quantitative assessment of cardiac motion in black blood cine tissue phase mapping (TPM) sequences. Up to now whole volume coverage of the heart is still limited by the long acquisition times. Therefore, a significant increase in imaging speed without deterioration of quantitative motion information is indispensable.
20 volunteers were enrolled in this study. Each volunteer underwent myocardial short-axis TPM scans with different SENSE acceleration factors. The influence of SENSE acceleration on the measured motion curves was investigated.
It is demonstrated that all TPM sequences with SENSE acceleration have only minimum influence on the motion curves. Even with a SENSE factor of four, the decrease in the amplitude of the motion curve was less than 3%. No significant difference was observed for the global correlation coefficient and deviation between the motion curves obtained by the reproducibility and the SENSE accelerated measurements.
It is feasible to accelerate myocardial TPM measurements with SENSE factors up to 4 without losing substantial information of the motion pattern.
本研究旨在探讨敏感度编码对黑血 Cine 组织相位图(TPM)序列中心脏运动定量评估的影响。到目前为止,心脏的全容积覆盖仍然受到采集时间长的限制。因此,在不降低定量运动信息质量的情况下,显著提高成像速度是必不可少的。
本研究纳入了 20 名志愿者。每位志愿者均进行了不同 SENSE 加速因子的心肌短轴 TPM 扫描。研究了 SENSE 加速对测量运动曲线的影响。
结果表明,所有具有 SENSE 加速的 TPM 序列对运动曲线只有最小的影响。即使 SENSE 因子为四,运动曲线的幅度下降也小于 3%。通过可重复性和 SENSE 加速测量获得的运动曲线的全局相关系数和偏差没有显著差异。
使用高达 4 的 SENSE 因子加速心肌 TPM 测量而不丢失运动模式的实质性信息是可行的。