Eldad A, Wisoki M, Cohen H, Breiterman S, Chaouat M, Wexler M R, Ben-Bassat H
Department of Plastic Surgery, Hadassah University Hospital, Jerusalem, Israel.
J Burn Care Rehabil. 1995 Jan-Feb;16(1):49-55. doi: 10.1097/00004630-199501000-00009.
White phosphorus is used in many types of military munitions, in fireworks, and in industrial and agricultural products. It ignites spontaneously and causes deep thermal injuries. It may also cause multiorgan failure because of its toxic effects on erythrocytes, liver, kidneys, and heart. Our previous studies demonstrated deleterious effects of copper sulfate. Only copious water irrigation was effective. This study examined other modalities of treatment and a free oxygen radical scavenger. One of the treatments seemed to have some beneficial effects, but simple water irrigation was much more effective. Superoxide dismutase, a free radical scavenger, reduced hepatic damage and adjacent skin flap destruction but did not prevent death of the animal receiving the high dose of white phosphorus used in the present setup.
白磷被用于多种军事弹药、烟花以及工农业产品中。它会自燃并导致深度热烧伤。由于其对红细胞、肝脏、肾脏和心脏的毒性作用，还可能导致多器官功能衰竭。我们之前的研究证明了硫酸铜的有害影响。只有大量水冲洗是有效的。本研究考察了其他治疗方式以及一种自由基清除剂。其中一种治疗似乎有一些有益效果，但单纯的水冲洗效果要好得多。超氧化物歧化酶，一种自由基清除剂，减轻了肝脏损伤和邻近皮瓣的破坏，但未能防止在本实验设置中接受高剂量白磷的动物死亡。
