Glauber H, Brown J
Center for Health Research, Kaiser Permanente Northwest Region, Portland, OR 97227-1908, USA.
J Clin Epidemiol. 1994 Oct;47(10):1133-42. doi: 10.1016/0895-4356(94)90100-7.
We studied the impact on annual medical care utilization and costs in 1988 of cardiovascular disease (CVD) in a population-based sample of 435 diabetic (DM) and 435 matched non-DM members of a Health Maintenance Organization. 58% of DM had at least one diagnosed CVD, compared to 26% of non-DM. 22.7% of outpatient visits, 38.7% of hospital days, and 30% of pharmacy expenditures by those with DM were primarily attributable to CVD. Up to 27% of all CABG recipients in the population had diabetes. In total, CVD directly accounted for at least 24% of total medical care costs among DM, compared to 12% of costs for non-DM. The HMO spent 4.5 times per person more on CVD care in DM than in non-DM members. Treatment with insulin was associated with increased peripheral vascular disease. After adjusting for age, CVD was more prevalent and generated longer hospital stays in DMs with nephropathy. The etiologic association between CVD and DM is well documented but CVD's clinical and economic importance in DM seems underappreciated.
我们在一个健康维护组织中,对435名糖尿病患者(DM)及435名匹配的非糖尿病成员进行了基于人群的抽样研究,以探讨1988年心血管疾病(CVD)对年度医疗服务利用和费用的影响。58%的糖尿病患者至少被诊断出患有一种心血管疾病,相比之下,非糖尿病患者的这一比例为26%。糖尿病患者门诊就诊的22.7%、住院天数的38.7%以及药房支出的30%主要归因于心血管疾病。该人群中高达27%的冠状动脉搭桥术(CABG)接受者患有糖尿病。总体而言,心血管疾病直接占糖尿病患者医疗总费用的至少24%,相比之下,非糖尿病患者的这一比例为12%。健康维护组织在糖尿病患者的心血管疾病护理方面人均支出比非糖尿病成员多4.5倍。胰岛素治疗与外周血管疾病增加有关。在调整年龄后,心血管疾病在患有肾病的糖尿病患者中更为普遍,且住院时间更长。心血管疾病与糖尿病之间的病因学关联已有充分记录,但心血管疾病在糖尿病中的临床和经济重要性似乎未得到充分重视。