Tsang P C, Samaranayake L P, Philipsen H P, McCulloug M, Reichart P A, Schmidt-Westhausen A, Scully C, Porter S R
Oral Biology Unit, University of Kong.
J Oral Pathol Med. 1995 Jan;24(1):32-6. doi: 10.1111/j.1600-0714.1995.tb01126.x.
Oral Candida albicans isolates from HIV-infected individuals in Hong Kong, Australia, Germany and England were characterised using a biotyping system based on enzyme profiles, carbohydrate assimilation patterns and boric acid resistance of the yeasts. A total of 44 biotypes were found amongst the 117 oral C. albicans isolates examined. The major biotype A1R accounted for 17.9% of all isolates while the second commonest biotype was A1S (11.1% of isolates). Whereas these two biotypes were isolated from all the regions studied, there were a number of other biotypes unique to individual countries. The data indicate that there are many different sub-strains of oral C. albicans in HIV-infected patients, some of which are globally prevalent. However, further work is required to ascertain the diversity of oral C. albicans biotypes, if any, in health and disease.
利用一种基于酵母的酶谱、碳水化合物同化模式和硼酸抗性的生物分型系统，对从香港、澳大利亚、德国和英国的HIV感染者中分离出的口腔白色念珠菌菌株进行了特征分析。在所检测的117株口腔白色念珠菌分离株中，共发现了44种生物型。主要生物型A1R占所有分离株的17.9%，第二常见的生物型是A1S（占分离株的11.1%）。虽然这两种生物型在所有研究地区均有分离，但还有许多其他生物型是个别国家所特有的。数据表明，HIV感染患者的口腔白色念珠菌有许多不同的亚菌株，其中一些在全球范围内普遍存在。然而，需要进一步开展工作，以确定健康和疾病状态下口腔白色念珠菌生物型（如果存在的话）的多样性。
