de Villiers F P
Department of Paediatrics and Child Health, University of the Witwatersrand Medical School, South Africa.
J Trop Pediatr. 1995 Feb;41(1):54-6. doi: 10.1093/tropej/41.1.54.
During diarrhoeal disease, stool mass is usually increased. Lactose content of stools and stool pH have been used as tests for secondary lactose maldigestion. The effect of a lactose-free diet and various lactose loads on the stools of 30 children with primary adult-type lactose maldigestion was investigated. Stool mass following the lactose tolerance test was the largest (mean = 80 g/day); that following the milk tolerance test less--62 g (not significantly), that on a milk containing diet significantly less (35 g), while stool mass produced on a lactose-free diet (22 g) was significantly less than that produced on any of the three lactose-containing diets. The stool pH on a milk containing diet (mean = 6.3) was significantly higher than those of the three other diets (after lactose tolerance test, pH = 5.85; after milk tolerance test, pH = 5.86; after lactose-free diet, pH = 5.83). Although stool bulk was greater when these lactose maldigesters were consuming a lactose containing diet, it was still considerably less than the stool mass associated with secondary lactose maldigestion, which is believed to be a cause of diarrhoeal disease. In contrast, the primary adult-type of lactose maldigestion does not commonly cause diarrhoea, as shown in this study.
在腹泻病期间，粪便量通常会增加。粪便中的乳糖含量和粪便pH值已被用作继发性乳糖消化不良的检测指标。研究了无乳糖饮食和不同乳糖负荷对30名原发性成人型乳糖消化不良儿童粪便的影响。乳糖耐量试验后的粪便量最大（平均 = 80克/天）；牛奶耐量试验后的粪便量较少——62克（无显著差异），含牛奶饮食时的粪便量显著更少（35克），而无乳糖饮食时产生的粪便量（22克）显著少于三种含乳糖饮食中的任何一种产生的粪便量。含牛奶饮食时的粪便pH值（平均 = 6.3）显著高于其他三种饮食（乳糖耐量试验后，pH = 5.85；牛奶耐量试验后，pH = 5.86；无乳糖饮食后，pH = 5.83）。尽管这些乳糖消化不良者食用含乳糖饮食时粪便量更大，但仍远低于与继发性乳糖消化不良相关的粪便量，继发性乳糖消化不良被认为是腹泻病的一个原因。相比之下，如本研究所示，原发性成人型乳糖消化不良通常不会引起腹泻。
