融合前培养的成肌细胞中乙酰胆碱受体的出现。
Appearance of acetylcholine receptors in cultured myoblasts prior to fusion.
作者信息
Teng N N, Fiszman M Y
出版信息
J Supramol Struct. 1976;4(3):381-7. doi: 10.1002/jss.400040309.
PMID:772316
Abstract
The development of the acetylcholine receptors in chick embryo myoblasts from 11-day old embryos was studied in vitro. Using the purified alpha-bungarotoxin labeled with radioactive iodide, a high concentration of acetylcholine receptors was found in the prefusing myoblasts; most of these receptors were located in the interior of the myoblasts. However, upon the completion of myoblasts fusion, the majority of the acetylcholine receptors appeared on the external cell surface of the myotubes.
摘要
对来自11日龄鸡胚的成肌细胞中乙酰胆碱受体的发育进行了体外研究。使用用放射性碘标记的纯化α-银环蛇毒素，发现预融合成肌细胞中存在高浓度的乙酰胆碱受体；这些受体大多位于成肌细胞内部。然而，成肌细胞融合完成后，大多数乙酰胆碱受体出现在肌管的细胞外表面。
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