Miyakawa T, Yagi T, Taniguchi M, Matsuura H, Tateishi K, Niki H
Department of Psychology, Faculty of Letters, University of Tokyo, Japan.
Brain Res Mol Brain Res. 1995 Feb;28(2):349-52. doi: 10.1016/0169-328x(94)00251-9.
Mice with a mutation in fyn genes were examined for their susceptibility to acoustically primed audiogenic seizures. Homozygous mutant (fynz/fynz) mice were significantly more likely to have seizures and to show the stronger seizure syndrome (clonus). These results indicate that the susceptibility of acoustically primed audiogenic seizures is enhanced in the Fyn kinase deficient mice.
对fyn基因发生突变的小鼠进行了声学引发的听源性癫痫易感性检测。纯合突变体（fynz/fynz）小鼠发生癫痫和表现出更强癫痫综合征（阵挛）的可能性显著更高。这些结果表明，Fyn激酶缺陷型小鼠对声学引发的听源性癫痫的易感性增强。
