Kanter D S, Horensky D, Sperling R A, Kaplan J D, Malachowski M E, Churchill W H
Neurology/Neurosurgery Intensive Care Unit, Brigham and Women's Hospital, Boston, MA 02115, USA.
Neurology. 1995 Apr;45(4):824-7. doi: 10.1212/wnl.45.4.824.
We describe two patients with fulminant acute disseminated encephalomyelitis (ADEM) treated with plasmapheresis after they failed to improve on steroids. Both patients improved concomitant with the plasma exchange. These are the first reported cases of fulminant ADEM with extensive white matter abnormalities on imaging studies treated with a regimen of plasmapheresis and steroids. Plasmapheresis may be beneficial in this disorder.
我们描述了两名暴发性急性播散性脑脊髓炎（ADEM）患者，他们在使用类固醇治疗后病情未改善，随后接受了血浆置换治疗。两名患者在血浆置换过程中病情均有改善。这是首次报道的经血浆置换和类固醇治疗方案治疗且影像学研究显示有广泛白质异常的暴发性ADEM病例。血浆置换可能对这种疾病有益。
