经胎儿直接给予腺苷以终止持续性室上性心动过速。
Direct fetal administration of adenosine for the termination of incessant supraventricular tachycardia.
作者信息
Kohl T, Tercanli S, Kececioglu D, Holzgreve W
机构信息
Department of Pediatric Cardiology, University of Münster, Germany.
出版信息
Obstet Gynecol. 1995 May;85(5 Pt 2):873-4. doi: 10.1016/0029-7844(94)00314-4.
BACKGROUND
Adenosine terminates supraventricular reentry tachycardia safely and effectively in the pediatric age group.
CASE
The recurrence of pretreated incessant tachycardia led to severe hydrops in a 28-week-old fetus. The tachycardia was terminated instantly with direct fetal administration of adenosine via the umbilical vein. Normal heart rate and rhythm were then preserved temporarily with digoxin and flecainide.
CONCLUSION
Direct fetal adenosine administration might be helpful in the treatment of fetal reentry tachycardias if the sinus rhythm achieved quickly can be preserved by long-acting antiarrhythmic drugs. Such a combined therapeutic approach might be especially advantageous in hydropic fetuses.
背景
腺苷可安全有效地终止小儿年龄组的室上性折返性心动过速。
病例
一名28周龄胎儿经治疗的持续性心动过速复发导致严重水肿。通过脐静脉直接向胎儿给药腺苷后，心动过速立即终止。随后用地高辛和氟卡尼暂时维持正常心率和节律。
结论
如果长效抗心律失常药物能够维持快速恢复的窦性心律，那么直接向胎儿给药腺苷可能有助于治疗胎儿折返性心动过速。这种联合治疗方法对于水肿胎儿可能特别有利。
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