Adelusi B, Osunkoya B O, Fabiyi A
Obstet Gynecol. 1976 May;47(5):545-8.
Exfoliated cells from the cervices of 22 patients with histologically diagnosed squamous cell carcinoma of the cervix and from those of 24 control women were examined for herpes subtype 2 (HT-2) antigens by indirect immunofluorescence studies. This method demonstrated that cells from all the patients with carcinoma contained antigens related to HT-2 virus. In contrast, squamous cells from the cervices of 24 control women with no cervical disease and of 2 women with chronic cervicitis did not contain such HT-2 antigens. Although an etiologic role of HT-2 virus infection cannot yet be established, it is probable that such infection precedes neoplastic changes.
对22例经组织学诊断为宫颈鳞状细胞癌患者的宫颈脱落细胞以及24例对照女性的宫颈脱落细胞进行间接免疫荧光研究，检测2型疱疹病毒（HT - 2）抗原。该方法表明，所有癌患者的细胞均含有与HT - 2病毒相关的抗原。相比之下，24例无宫颈疾病的对照女性以及2例患有慢性宫颈炎女性的宫颈鳞状细胞中未含有此类HT - 2抗原。虽然尚未确定HT - 2病毒感染的病因学作用，但这种感染很可能先于肿瘤性改变发生。
