Konovalov A, Gorelyshev S, Serova N
Burdenko Institute of Neurosurgery, Moscow, Russia.
Acta Neurochir (Wien). 1994;130(1-4):71-9. doi: 10.1007/BF01405505.
During a period of 17 years (from 1976 till now) 45 patients with giant gliomas of the chiasma and the IIIrd ventricle out of a total amount of 120 patients with hypothalamic gliomas were operated. The following classification of tumours was used: I) tumours with predominant anterior growth; II) tumours which infiltrate chiasma and penetrate into the IIIrd ventricle; III) gliomas of the floor of the IIIrd ventricle and the chiasma, growing into the ventricle cavity; IV) tumours of the chiasma, optic tract and thalamus. The authors come to the conclusion, that surgical removal of giant tumours of the chiasma and the IIIrd ventricle, though risk, may result in an improvement or stabilisation of visual functions (77%) and a long period free from recurrencies (9.5%). The postoperative period is relatively favourable and the mortality is low (6%). The main contraindication in our opinion is a wide infiltration of adjacent brain structures by the tumour and spreading along both optical tracts. We consider the giant size of a tumour in itself a sufficient indication for surgery.
在17年期间(从1976年至今),120例下丘脑胶质瘤患者中有45例患有视交叉和第三脑室的巨大胶质瘤并接受了手术。采用了以下肿瘤分类:I)以向前生长为主的肿瘤;II)浸润视交叉并侵入第三脑室的肿瘤;III)第三脑室底部和视交叉的胶质瘤,向脑室腔内生长;IV)视交叉、视束和丘脑的肿瘤。作者得出结论,尽管有风险,但对视交叉和第三脑室的巨大肿瘤进行手术切除可能会改善或稳定视觉功能(77%),并实现长期无复发(9.5%)。术后恢复相对良好,死亡率较低(6%)。我们认为主要的禁忌症是肿瘤广泛浸润相邻脑结构并沿双侧视束扩散。我们认为肿瘤本身体积巨大足以作为手术指征。