• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Inhibition of arachidonic acid cyclo-oxygenase and lipoxygenase activities of leukocytes by indomethacin and compound BW755C. 1980.

作者信息

Randall R W, Eakins K E, Higgs G A, Salmon J A, Tateson J E

出版信息

Agents Actions. 1994 Dec;43(3-4):176-8; discussion 167. doi: 10.1007/BF01986685.

DOI:10.1007/BF01986685
PMID:7725969
Abstract
摘要

相似文献

1
Inhibition of arachidonic acid cyclo-oxygenase and lipoxygenase activities of leukocytes by indomethacin and compound BW755C. 1980.
Agents Actions. 1994 Dec;43(3-4):176-8; discussion 167. doi: 10.1007/BF01986685.
2
Inhibition of arachidonic acid cyclo-oxygenase and lipoxygenase activities of leukocytes by indomethacin and compound BW755C.吲哚美辛和化合物BW755C对白细胞花生四烯酸环氧化酶和脂氧化酶活性的抑制作用。
Agents Actions. 1980 Dec;10(6):553-5. doi: 10.1007/BF02024164.
3
Suppression of experimental autoimmune encephalomyelitis by dual cyclo-oxygenase and 5-lipoxygenase inhibition.通过双重抑制环氧化酶和5-脂氧合酶抑制实验性自身免疫性脑脊髓炎
Acta Neurol Scand. 1989 Mar;79(3):223-6. doi: 10.1111/j.1600-0404.1989.tb03742.x.
4
Interdependence of contractile responses of rat small mesenteric arteries on nitric oxide and cyclo-oxygenase and lipoxygenase products of arachidonic acid.大鼠小肠系膜动脉收缩反应对一氧化氮、花生四烯酸环氧化酶和脂氧合酶产物的相互依赖性。
Br J Pharmacol. 1994 Jun;112(2):360-8. doi: 10.1111/j.1476-5381.1994.tb13080.x.
5
Arachidonic acid-induced pleurisy (ARIP): an in vivo model for testing 5-lipoxygenase inhibition.
Methods Find Exp Clin Pharmacol. 1987 Dec;9(12):793-7.
6
Reduction of apparent indicators of liver cirrhosis in rats by the arachidonate lipoxygenase inhibitor BW755C.花生四烯酸脂氧合酶抑制剂BW755C降低大鼠肝硬化的表观指标
Eur J Pharmacol. 1987 Feb 10;134(2):175-80. doi: 10.1016/0014-2999(87)90163-4.
7
Meclofenamate sodium is an inhibitor of both the 5-lipoxygenase and cyclooxygenase pathways of the arachidonic acid cascade in vitro.甲氯芬那酸钠在体外是花生四烯酸级联反应中5-脂氧合酶和环氧化酶途径的抑制剂。
Prostaglandins Leukot Med. 1986 Aug;23(2-3):229-38. doi: 10.1016/0262-1746(86)90190-3.
8
Relative roles of nitric oxide and cyclo-oxygenase and lipoxygenase products of arachidonic acid in the contractile responses of rat renal arcuate arteries.一氧化氮、花生四烯酸的环氧化酶和脂氧化酶产物在大鼠肾弓状动脉收缩反应中的相对作用。
Br J Pharmacol. 1994 Jun;112(2):369-76. doi: 10.1111/j.1476-5381.1994.tb13081.x.
9
Inflammatory properties of lipoxygenase products and the effects of indomethacin and BW755C on prostaglandin production, leukocyte migration, and plasma exudation in rabbit skin.脂氧合酶产物的炎症特性以及消炎痛和BW755C对兔皮肤中前列腺素生成、白细胞迁移和血浆渗出的影响。
Adv Prostaglandin Thromboxane Leukot Res. 1982;9:331-9.
10
Inhibition of mononuclear leukocyte accumulation by the arachidonic acid lipoxygenase inhibitor BW755C.花生四烯酸脂氧合酶抑制剂BW755C对单核白细胞聚集的抑制作用。
Adv Prostaglandin Thromboxane Leukot Res. 1983;12:19-23.

引用本文的文献

1
Dual 12/15- and 5-lipoxygenase deficiency in macrophages alters arachidonic acid metabolism and attenuates peritonitis and atherosclerosis in ApoE knock-out mice.巨噬细胞中双重12/15-脂氧合酶和5-脂氧合酶缺乏会改变花生四烯酸代谢，并减轻载脂蛋白E基因敲除小鼠的腹膜炎和动脉粥样硬化。
J Biol Chem. 2009 Jul 31;284(31):21077-89. doi: 10.1074/jbc.M109.000901. Epub 2009 Jun 9.

本文引用的文献

1
Aspirin-like drugs inhibit arachidonic acid metabolism via lipoxygenase and cyclo-oxygenase in rat neutrophils from carrageenan pleural exudates.
Biochem Biophys Res Commun. 1980 Jan 29;92(2):688-95. doi: 10.1016/0006-291x(80)90388-5.
2
Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs.抑制前列腺素合成作为阿司匹林类药物的作用机制。
Nat New Biol. 1971 Jun 23;231(25):232-5. doi: 10.1038/newbio231232a0.
3
Transformation of arachidonic acid and homo-gamma-linolenic acid by rabbit polymorphonuclear leukocytes. Monohydroxy acids from novel lipoxygenases.兔多形核白细胞对花生四烯酸和高γ-亚麻酸的转化。新型脂氧合酶产生的单羟基酸。
J Biol Chem. 1976 Dec 25;251(24):7816-20.
4
Biogenesis of chemotactic molecules by the arachidonate lipoxygenase system of platelets.血小板花生四烯酸脂氧合酶系统产生趋化分子的过程。
Nature. 1975 Oct 23;257(5528):680-1. doi: 10.1038/257680a0.
5
Leukotriene C: a slow-reacting substance from murine mastocytoma cells.白三烯C：一种来自小鼠肥大细胞瘤细胞的慢反应物质。
Proc Natl Acad Sci U S A. 1979 Sep;76(9):4275-9. doi: 10.1073/pnas.76.9.4275.