Boone M, Dangoisse C, André J, Sass U, Song M, Ledoux M
Clinic of Dermatology, University Hospital Saint-Pierre, University of Brussels, Belgium.
Dermatology. 1995;190(2):164-8. doi: 10.1159/000246670.
Three children will be described who present recurrent episodes of pruritic papulopustular follicular lesions on the face, the extremities and the trunk. The episodes lasted for 1-3 months with intermittent remission. Each flare was accompanied by hypereosinophilia and an increased total IgE titer. RAST and prick tests were positive for Dermatophagoides pteronyssinus (DPT). Laboratory tests disclosed no infectious or parasitic etiology. Histological examination showed eosinophilic pustular folliculitis (EPF) in each of the 3 cases. The lesions responded well to topical corticosteroids. The aim of this article is to underline the importance of hypersensitivity reactions (in these particular cases to DPT) in the pathogenesis of EPF.
将描述三名儿童，他们面部、四肢和躯干出现反复的瘙痒性丘疹脓疱性毛囊病变。发作持续1至3个月，有间歇性缓解。每次发作都伴有嗜酸性粒细胞增多和总IgE滴度升高。针对屋尘螨（DPT）的放射性变应原吸附试验（RAST）和点刺试验呈阳性。实验室检查未发现感染性或寄生虫病因。组织学检查显示3例均为嗜酸性脓疱性毛囊炎（EPF）。病变对局部皮质类固醇反应良好。本文的目的是强调超敏反应（在这些特定病例中对DPT的超敏反应）在EPF发病机制中的重要性。
