Benner E J, Kranhold J F, Bush W G
Scott Med J. 1976 Sep;20(5):244-7. doi: 10.1177/003693307502000514.
Cephazolin sodium was shown to be as effective as ampicillin in the treatment of respiratory and urinary system infections in patients who were infected with susceptible organisms and had a much less troublesome side reaction rate of hypersensitivity type. In addition, it was found that predictable blood levels of cephazolin could be obtained in patients with renal failure when dosage was regulated according to a nomogram calculated from the patient's serum half-life based on clearance of creatinine.
头孢唑林钠在治疗感染了敏感菌的患者的呼吸系统和泌尿系统感染方面，被证明与氨苄西林一样有效，且过敏型副作用发生率低得多。此外，还发现对于肾衰竭患者，根据由患者血清半衰期（基于肌酐清除率计算）得出的列线图来调整剂量时，可获得可预测的头孢唑林血药浓度。
