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查尔斯·博内综合征:荷兰的一项大型前瞻性研究。一项针对奈梅亨大学眼科系500名患者的查尔斯·博内综合征患病率及相关因素的研究。

The Charles Bonnet syndrome: a large prospective study in The Netherlands. A study of the prevalence of the Charles Bonnet syndrome and associated factors in 500 patients attending the University Department of Ophthalmology at Nijmegen.

作者信息

Teunisse R J, Cruysberg J R, Verbeek A, Zitman F G

机构信息

Department of Psychiatry, University Hospital Nijmegen, The Netherlands.

出版信息

Br J Psychiatry. 1995 Feb;166(2):254-7. doi: 10.1192/bjp.166.2.254.

DOI:10.1192/bjp.166.2.254
PMID:7728372
Abstract

BACKGROUND

The aims were to determine the prevalence of the Charles Bonnet syndrome (CBS) in low-vision patients and analyse possible associated ophthalmic and sociodemographic factors.

METHOD

A semi-structured interview on visual hallucinations was given to 300 adult low-vision patients and 200 elderly general ophthalmic patients. Positive cases were examined with the Geriatric Mental State Schedule and the Mini Mental State Examination. Diagnostic criteria were as follows: complex, persistent, or repetitive visual hallucinations; full or partial retention of insight; no hallucinations in other modalities; and no delusions. Ophthalmic and sociodemographic data were gathered for all patients.

RESULTS

The prevalence of CBS in low-vision patients was 11%. CBS was significantly associated with an age over 64 years and a visual acuity in the best eye of 0.3 or less. No significant associations with ophthalmic diagnoses, patient sex, marital status, or social circumstances were found.

CONCLUSION

Our findings support association of CBS with sensory deprivation and advanced age.

摘要

背景

目的是确定低视力患者中查尔斯·邦尼特综合征(CBS)的患病率,并分析可能相关的眼科及社会人口学因素。

方法

对300名成年低视力患者和200名老年普通眼科患者进行了关于视幻觉的半结构化访谈。对阳性病例采用老年精神状态检查表和简易精神状态检查表进行检查。诊断标准如下:复杂、持续或反复出现的视幻觉;完全或部分保持自知力;无其他形式的幻觉;无妄想。收集了所有患者的眼科及社会人口学数据。

结果

低视力患者中CBS的患病率为11%。CBS与64岁以上年龄以及最佳眼视力为0.3或更低显著相关。未发现与眼科诊断、患者性别、婚姻状况或社会环境有显著关联。

结论

我们的研究结果支持CBS与感觉剥夺和高龄相关。

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