New glycosidases inhibitors, panosialins D and wD produced by Streptomyces sp. OH-5186.
作者信息
Yamada H, Shiomi K, Xu Q, Nagai T, Shibata M, Oya I, Takahashi Y, Omura S
机构信息
Research Center for Biological Function, Kitasato Institute, Tokyo, Japan.
出版信息
J Antibiot (Tokyo). 1995 Mar;48(3):205-10. doi: 10.7164/antibiotics.48.205.
PMID:7730153
Abstract
New panosialin analog, panosialins D and wD have been isolated from the culture broth of Streptomyces sp. OH-5186. Their structures were elucidated as 5-(13-methylpentadecyl)-1,3-benzenediol bis(sodium sulfate) and 5-(13-methylpentadecyl)-1,3-benzenediol 1-(sodium sulfate), respectively. They showed strong inhibitory activity against alpha-mannosidase, alpha-glucosidase, and beta-glucosidase. Panosialins wA-wD mixture also showed weak mitogenic activity but suppressed the mitogen induced activity.
摘要
相似文献
1
New glycosidases inhibitors, panosialins D and wD produced by Streptomyces sp. OH-5186.
J Antibiot (Tokyo). 1995 Mar;48(3):205-10. doi: 10.7164/antibiotics.48.205.
2
FR191512, a novel anti-influenza agent isolated from a fungus strain No.17415. I. Taxonomy, fermentation, isolation, physico-chemical properties and structure elucidation.
J Antibiot (Tokyo). 2000 Dec;53(12):1333-40. doi: 10.7164/antibiotics.53.1333.
3
A new antiherpetic agent produced by Streptomyces sp. strain no. 758.由链霉菌属菌株758产生的一种新型抗疱疹剂。
J Antibiot (Tokyo). 1995 Nov;48(11):1234-9. doi: 10.7164/antibiotics.48.1234.
4
A new antiherpetic agent, AH-135Y, produced by Streptomyces albovinaceus strain No. AH-135.一种由白色产色链霉菌AH-135菌株产生的新型抗疱疹剂AH-135Y。
J Antibiot (Tokyo). 1992 Aug;45(8):1370-2. doi: 10.7164/antibiotics.45.1370.
5
Boromycin, an anti-HIV antibiotic.
Biosci Biotechnol Biochem. 1996 Jun;60(6):1036-7. doi: 10.1271/bbb.60.1036.
6
An enzyme inhibitor, panosialin, produced by Streptomyces. I. Biological activity, isolation and characterization of panosialin.一种由链霉菌产生的酶抑制剂——泛唾液酸酶。I. 泛唾液酸酶的生物活性、分离与特性
J Antibiot (Tokyo). 1971 Dec;24(12):860-9. doi: 10.7164/antibiotics.24.860.
7
Siamycins I and II, new anti-HIV peptides: I. Fermentation, isolation, biological activity and initial characterization.暹罗霉素I和II，新型抗HIV肽：I. 发酵、分离、生物活性及初步表征
J Antibiot (Tokyo). 1995 May;48(5):433-4. doi: 10.7164/antibiotics.48.433.
8
AM-2604 A, a new antiviral antibiotic produced by a strain of Streptomyces.AM - 2604 A，一种由链霉菌菌株产生的新型抗病毒抗生素。
J Antibiot (Tokyo). 1982 Dec;35(12):1632-7. doi: 10.7164/antibiotics.35.1632.
9
Enopeptin A, a novel depsipeptide antibiotic with anti-bacteriophage activity.
J Antibiot (Tokyo). 1991 Dec;44(12):1463-6. doi: 10.7164/antibiotics.44.1463.
10
Novel glycosidase inhibitors, nojirimycin B and D-mannonic-delta-lactam. Isolation, structure determination and biological property.新型糖苷酶抑制剂，野尻霉素B和D-甘露糖酸-δ-内酰胺。分离、结构测定及生物学特性。
J Antibiot (Tokyo). 1984 Dec;37(12):1579-86. doi: 10.7164/antibiotics.37.1579.
引用本文的文献
1
Sulfotanone, a new alkyl sulfonic acid derivative from Streptomyces sp. IFM 11694 with TRAIL resistance-overcoming activity.磺基他农，一种来自链霉菌属IFM 11694的具有克服TRAIL抗性活性的新型烷基磺酸衍生物。
J Nat Med. 2016 Apr;70(2):266-70. doi: 10.1007/s11418-015-0951-3. Epub 2015 Nov 25.
2
An expedient synthesis of 5-n-alkylresorcinols and novel 5-n-alkylresorcinol haptens.5-正烷基间苯二酚的简便合成及新型 5-正烷基间苯二酚半抗原。
Beilstein J Org Chem. 2009 May 19;5:22. doi: 10.3762/bjoc.5.22.
3
Panosialins, inhibitors of an alpha1,3-fucosyltransferase Fuc-TVII, suppress the expression of selectin ligands on U937 cells.
Glycoconj J. 1998 Nov;15(11):1079-83. doi: 10.1023/a:1006953626578.
Zotero 插件