AM - 2604 A，一种由链霉菌菌株产生的新型抗病毒抗生素。
AM-2604 A, a new antiviral antibiotic produced by a strain of Streptomyces.
作者信息
Omura S, Shimizu H, Iwai Y, Hinotozawa K, Otoguro K, Hashimoto H, Nakagawa A
出版信息
J Antibiot (Tokyo). 1982 Dec;35(12):1632-7. doi: 10.7164/antibiotics.35.1632.
PMID:7166528
Abstract
A novel antibiotic, AM-2604 A was isolated from the fermentation broth of Streptomyces sp. AM-2604 by solvent extraction and silica gel column chromatography. The antibiotic is pale yellow needles possessing UV absorption maxima at 280 nm and 330 nm (sh). The antibiotic possesses weak activity against fungi and trichomonad and potent inhibitory activity against various RNA and DNA viruses in vitro.
摘要
一种新型抗生素AM-2604 A是从链霉菌属AM-2604的发酵液中通过溶剂萃取和硅胶柱色谱法分离得到的。该抗生素为浅黄色针状晶体，在280 nm和330 nm（肩峰）处有最大紫外吸收。该抗生素对真菌和滴虫具有较弱的活性，在体外对各种RNA和DNA病毒具有较强的抑制活性。
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