Uyeda M, Kondo K I, Ito A, Yokomizo K, Kido Y
Faculty of Pharmaceutical Sciences, Kumamoto University, Japan.
J Antibiot (Tokyo). 1995 Nov;48(11):1234-9. doi: 10.7164/antibiotics.48.1234.
A new antiherpetic agent, AH-758, was isolated from the culture broth of Streptomyces sp. strain No. 758. The structure was determined by NMR special analyses to be a new antibiotic belonging to bafilomycin group containing (5-oxo-2-pyrrolin-2-yl) methyl fumarate in its C-21.
一种新型抗疱疹剂AH-758,是从链霉菌属758号菌株的培养液中分离得到的。通过核磁共振谱特殊分析确定其结构,它是一种属于巴弗洛霉素类的新型抗生素,在其C-21位含有富马酸(5-氧代-2-吡咯啉-2-基)甲酯。